Premedication Instructions for Patients with Contrast Allergies

Prednisone 50mg po at 13 hours, 7 hours and 1 hour prior to planned administration of intravenous contrast plus diphenhydramine 50mg po, iv or im at 1 hour prior to planned administration of intravenous contrast

Or

Methylprednisolone 32mg po at 12 hours and 2 hours prior to planned administration of contrast plus diphenhydramine 50 mg po, iv or im at 1 hour prior to the planned administration of contrast

Or

Hydrocortisone 200mg iv at 13 hours, 7 hours and 1 hour prior to planned administration of intravenous contrast if patient is unable to take po medications

Creatinine Testing Prior to Contrast Administration

Routine creatinine testing prior to contrast administration is not necessary in all patients. The major indications are age over 60, history of renal insufficiency, diabetes mellitus, or hypertension.